.png)
Ozempic, originally developed for the treatment of Type 2 diabetes, is now a widely recognized medication. It can be confidently stated that it is an innovative tool that has made diabetes management significantly easier.
However, its growing popularity is not only due to this—Ozempic injections are also used for weight loss. The effect is so impressive that it is virtually equal to the results achieved through bariatric surgery. Consequently, the demand for the drug has increased substantially.
Of course, like any potent pharmacological agent, Ozempic has side effects and carries certain risks. To avoid potential complications, it is crucial to be well-informed.
This blog serves as a guide to help you identify, manage, and prevent potential problems associated with Ozempic treatment. It discusses common side effects, serious risks, and the correct administration of the drug.
Ozempic belongs to a class of drugs called GLP-1 receptor agonists. Its effectiveness is determined by its active ingredients.
The main active component of Ozempic is Semaglutide. It regulates blood sugar levels, reduces appetite, decreases the desire for food intake, slows gastric emptying, and helps the body control weight and utilize insulin more effectively.
In addition to semaglutide, the Ozempic injection pen contains several inactive ingredients:
Phenol solution – protects the drug from microbial contamination.
Methionine – helps maintain the stability of the solution.
Disodium phosphate (phosphate buffer) – maintains the correct pH level.
Water for injection – the primary solvent.
Micro-doses of hydrochloric acid or sodium hydroxide – used to adjust the acidity of the solution.
Therefore, Semaglutide is the only active substance in Ozempic, while the other components ensure the stability, safety, and painlessness of the injection. Notably, its composition does not include sugar, insulin, caffeine, fat, or hormones.
Like all medications, Ozempic is characterized by side effects, which are primarily caused by its action on the gastrointestinal system.
Common side effects include:
Nausea: The most frequent complaint.
Vomiting and Diarrhea: May manifest acutely.
Constipation: Slowing of bowel movements.
Abdominal bloating or pain.
These symptoms occur in most patients, especially at the start of treatment or during dose increases. Usually, they are mild and temporary. Furthermore, their appearance is often a sign that the body is adapting to the medication.
General complaints not directly related to the gastrointestinal tract are also common:
Headache or dizziness.
Fatigue or weakness.
Pain, itching, or redness at the injection site.
There are serious risks and symptoms that require immediate attention. Although such side effects are rare, knowing about them is vital.
Pancreatitis: Inflammation of the pancreas is a serious, potentially life-threatening condition that can develop while taking Ozempic. Symptoms include severe, persistent pain in the upper abdomen that often radiates to the back, accompanied by vomiting and fever. If symptoms of pancreatitis appear, stop taking Ozempic immediately and consult a doctor.
Thyroid C-cell tumors: A potential risk has been identified. Studies have shown that GLP-1 agonists caused medullary thyroid cancer (MTC) in animals. This risk is not confirmed in humans, but doctors take the issue seriously. If you notice a lump in your neck, hoarseness, or difficulty swallowing, consult a doctor immediately.
Severe Hypoglycemia and Kidney Damage:
Hypoglycemia: The risk of a sharp drop in blood sugar increases if Ozempic is taken with insulin or sulfonylureas. Symptoms include cold sweats, shaking, and anxiety. In such cases, it is necessary to consume a sugary drink or glucose tablets.
Acute Kidney Injury: Persistent diarrhea and vomiting accompanied by dehydration can lead to worsening kidney function. It is important to stay hydrated and inform your doctor if nausea or vomiting becomes unmanageable.
To ensure the success of the treatment course, proper prescription, dosage, and storage are essential.
The drug is taken once a week via subcutaneous injection—into the abdomen, thigh, or upper arm. Check the Ozempic pen before use and use a new needle for every injection. To avoid local skin reactions like burning or irritation, rotate the injection site.
Adherence to the dosage is critical. You must not change the dose yourself. If your doctor has prescribed Ozempic 1 mg, follow this instruction strictly.
Regarding missed doses: If you forget a dose and there are more than 5 days until the next scheduled dose, take the missed dose immediately. If fewer than 5 days remain, skip the missed dose and proceed with the next scheduled one.
Compliance with storage rules is necessary for the drug's efficacy and safety.
Unopened pens should be stored in the refrigerator at 2°C - 8°C. Do not freeze, as low temperatures damage semaglutide. Keep the medication away from direct sunlight and heat.
After opening, Ozempic can be stored in the refrigerator or at room temperature (up to 30°C). An opened pen is valid for 56 days (8 weeks); after this, it is no longer safe to use.
Do not use if the liquid has changed color or consistency, if the pen has been frozen, or if 56 days have passed since opening.
Always remove the needle after each injection and replace the pen cap for protection.
Managing the course correctly is paramount since Ozempic affects not only blood sugar but also digestion, hormonal functions, and metabolism. Proper management involves medical supervision, dose control, timely assessment of side effects, and maintaining a healthy lifestyle.
Ozempic is not just a "weight loss shot." It should only be used as prescribed by an endocrinologist or qualified physician. Unauthorized use can lead to hormonal imbalances, pancreatitis, dehydration, and other serious complications.
The dosage schedule usually starts at 0.25 mg, then increases to 0.5 mg, and only reaches 1 mg or more upon a doctor's recommendation. Rapid dose changes pose the highest risk for severe nausea, vomiting, and pancreatitis.
Lifestyle and Monitoring:
Avoid fatty and heavy foods as the stomach empties more slowly.
Drink 1.5 - 2 liters of fluids daily to prevent dehydration.
Eat protein and fiber-rich foods to reduce nausea.
Monitor liver and pancreas function, especially if you have a history of gallbladder issues or pancreatitis.
Contraindications:
Ozempic should not be used by individuals under 18, or during pregnancy and lactation.
It is not used for Type 1 diabetes.
Psychological and nutritional habits should be monitored to prevent total food rejection due to suppressed appetite.
Discontinuation: Stopping the medication should be done gradually. Otherwise, intense appetite may return, leading to sharp increases in blood sugar or rapid weight regain.
Ozempic 1 mg is a powerful tool against diabetes and obesity. However, using it without strict medical supervision is unacceptable. Follow the administration rules and consult a specialist immediately if complications arise. Your safety and health must remain the priority.
