Paracetamol is used to relieve fever and pain. The therapeutic dose depends on age and weight.
Paracetamolum
Paracetamol; Para-acetaminophenol.
Clear, viscous, pink, sweet-tasting syrup with a characteristic raspberry scent.
100 ml syrup contains:2.4 g Paracetamol.
Excipients:Propylene glycol, glycerin, ethyl alcohol, powdered food sorbitol, nipagin (methylparaben), nipazol (propylparaben), raspberry aromatic food essence, light red-crimson C 121 dye, and purified water.
Syrup
Anti-inflammatory, analgesic, and antipyretic agent.
Pain syndrome of various origins, minor and medium intensity:
Headache, toothache, neuralgia, myalgia.
Pain caused by teething.
During injuries, burns, pharyngitis, rheumatic pains.
As well as:
Fever caused by infectious and inflammatory diseases.
During childhood viral infections.
The medicine is prescribed for internal use. Frequency of administration is 3–4 times per day, with an interval of no less than 4 hours between each dose.
Dosing by Age:
Children aged 6 months to 1 year: 2.5–5 ml syrup (0.5–1 teaspoon).
Children aged 1 to 3 years: 5–7.5 ml syrup (1–1.5 teaspoons).
Children aged 3 to 6 years: 7.5–10 ml (1.5–2 teaspoons).
Children aged 6 to 12 years: 10–15 ml (2–3 teaspoons).
Children over 12 years of age: 15–25 ml (3–4 teaspoons).
In case of hypersensitivity to Paracetamol, the following may occur: Nausea, pain in the epigastric region, allergic reactions (skin rash, itching, urticaria, Quincke's edema).
In case of exceeding the recommended dose of syrup, the following adverse effects may develop: Hemolytic anemia, thrombocytopenic purpura, methemoglobinemia, agranulocytosis.
During prolonged administration of a dose exceeding the therapeutic one: Hepatotoxic action is possible.
Hypersensitivity to Paracetamol.
Pronounced impairment of liver and kidney function.
Glucose-6-phosphate dehydrogenase deficiency.
Blood diseases.
Children under 6 months of age.
Patients using barbiturates and tricyclic antidepressants while using Paracetamol may experience an increase in the half-life of the latter.
Prolonged use of anticonvulsant drugs leads to an increase in liver enzyme activity, which enhances the "first-pass" effect in the liver and leads to increased drug clearance. This may hinder the achievement of a therapeutic level of Paracetamol concentration in the blood.
