It is used in cases of immediate-type allergic reactions, bronchial asthma, and arterial hypotension of various origins.
Active substance: Epinephrine.
1 ml of solution contains 1.82 mg of epinephrine hydrotartrate.
Excipients: Sodium metabisulfite (E223), sodium chloride, water for injection.
Immediate-type allergic reactions: anaphylactic shock caused by medications, serums, blood transfusions, insect bites, or allergen exposure.
Bronchial asthma – relief of acute attacks.
Arterial hypotension of various origins (post-hemorrhagic, toxic, infectious).
Hypoglycemia due to insulin overdose.
Asystole, cardiac arrest.
Prolongation of local anesthetic effects.
Asystole, including that occurring in the setting of third-degree AV block.
Hypersensitivity to the components of the preparation
Hypertrophic obstructive cardiomyopathy
Severe aortic stenosis
Tachyarrhythmia
Ventricular fibrillation
Pheochromocytoma
Closed-angle glaucoma
Shock (except anaphylactic)
General anesthesia with inhalation agents: fluorothane, cyclopropane, chloroform
Second stage of labor
Injection into fingers, toes, nose, genital area
Adults:
Anaphylactic shock: Administer 0.5 ml slowly IV, diluted in 20 ml of 40% glucose solution. If necessary, continue with IV infusion at 1 mcg/min, by diluting 1 ml of adrenaline in 400 ml of isotonic sodium chloride or 5% glucose. If the patient’s condition allows, IM or SC injection of 0.3–0.5 ml (diluted or undiluted) is preferred.
Bronchial asthma: Administer 0.3–0.5 ml SC (diluted or undiluted). If needed, repeat every 20 minutes (up to 3 times). IV administration of 0.3–0.5 ml (diluted) is also possible. As a vasoconstrictor, it can be infused IV at 1 mcg/min (increasing up to 2–10 mcg/min if necessary).
Asystole: Inject 0.5 ml intracardially, diluted in 10 ml of 0.9% sodium chloride. During resuscitation: 1 ml (diluted) IV slowly every 3–5 minutes.
Children:
Asystole in newborns: Administer 10–30 mcg/kg IV slowly every 3–5 minutes.
Anaphylactic shock: Administer 10 mcg/kg SC or IM (max 0.3 mg); repeat every 15 minutes if needed (up to 3 times).
Bronchospasm: Administer 10 mcg/kg SC (max 0.3 mg); repeat every 15 minutes (3–4 times) or every 4 hours.
Store in the original packaging at temperatures not exceeding 25°C.
Keep out of reach of children.